Fen-Phen

Fen-Phen is a cocktail of the drugs fenfluramine and phentermine used to aid weight loss. Fenfluramine and phentermine had been approved for separate, short-term use for about 20 years when the FDA approved Redux or dexfenfluramine in 1996. Fen-Phen was withdrawn from the market after if was found that about 30 percent of users had abnormal echocardiograms. Fen-Phen has been linked to serious cardiac problems, including heart murmurs, heart valve leaks, heart valve thickening, heart valve regurgitation, primary pulmonary hypertension and sometimes death. More than 50,000 lawsuits have been filed by Fen-Phen users against the drugs’ manufacturers.

Fast Facts

Name: Fen-phen
Generic: Fenfluramine and dexfenfluramine
Manufacturer: Wyeth-Ayerst Laboratories
Date approved: Redux (dexfenfluramine) approved April 1996
Status: Withdrawn from market
Approved uses: Weight loss
Off-Label uses: N/A
Side effects: Heart murmurs, heart valve leaks, heart valve thickening, heart valve regurgitation, primary pulmonary hypertension
Related topics: Unsafe drugs, ephedra

Dangerous Diet Pills: The Side Effects of Fen-Phen

As Americans, we value efficiency and we place considerable emphasis on the necessity of beauty and health. In our fast-paced world, a healthy diet and lifestyle can sometimes take a back seat to... read more

Fen-Phen and Redux -- Withdrawn From Market

The diet drugs Fen-Phen (fenfluramine and phentermine), Pondimin (fenfluramine), and Redux (dexfenfluramine) aid in weight loss by altering the serotonin levels... read more

View the Fen-Phen Main Articles page here


Jury Verdicts Related to Fen-Phen

______ VERDICT INCLUDING $20,000,000 IN PUNITIVE DAMAGES (case subsequently settles for undisclosed sum) - PRODUCTS LIABILITY - MAJOR PHARMACEUTICAL COMPANY ALLEGEDLY LIABLE FOR PERMANENT HEART DAMAGE SUFFERED BY FEMALE PLAINTIFF ATTRIBUTABLE TO FEN-PHEN DIET DRUG MANUFACTURED AND MARKETED BY THE DEFENDANT - PLAINTIFF ALLEGED THAT THE DEFENDANT AMERICAN HOME PRODUCTS KNEW THAT ITS DRUG WAS UNSAFE AND CONTINUED TO MANUFACTURE AND MARKET THE DRUG REGARDLESS - HEART VALVE DAMAGE.

View the Fen-Phen Jury Verdicts page here


FDA Information Related to Fen-Phen

CDER Index A-F

"FEN-PHEN" UPDATE

View the Fen-Phen FDA Information page here


MSN Newsfeeds Related to Fen-Phen

Curlin Wins 2 Eclipse Awards

Multimillion-dollar bond for Curlin co-owners

View the Fen-Phen MSN Newsfeeds page here


News Articles Related to Fen-Phen

The Associated Press: Judge won't hear fen-phen settlement fraud retrial

Law.com - Lawyer Calls Former Paralegal's 'Sexual Predator' Claims 'Ridiculous and Not True'

View the Fen-Phen News Articles page here


Useful Web Sites Related to Fen-Phen

Burg Simpson, Unsafe Drugs Attorneys

Anapol Schwarz, Fen-Phen Attorneys

View the Fen-Phen Useful Web Sites page here


Wikipedia Entries Related to Fen-Phen

Fen-phen

Fenfluramine

View the Fen-Phen Wikipedia Entries page here


Books Related to Fen-Phen

Dispensing with the Truth : The Victims, the Drug Companies, and the Dramatic Story Behind the Battle over Fen-Phen

Safer Than Phen-Fen!

View the Fen-Phen Books page here

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